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Telomeric Repeat-Containing RNA (TERRA) and Telomerase Are Components of Telomeres During Mammalian Gametogenesis1

10 Apr 2014

Abstract excerpt

Telomeres are ribonucleoprotein structures at the end of chromosomes composed of telomeric DNA, specific-binding proteins, and noncoding RNA (TERRA). Despite their importance in preventing chromosome instability, little is known about the cross talk between these three elements during the formation of the germ line. Here, we provide evidence that both TERRA and the telomerase enzymatic subunit (TERT) are...

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Share to Chromosomal and Genetic Variations
Share to Genetics, Aging, and Longevity in Model Organisms
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 24719256
DOI: 10.1095/biolreprod.113.116954

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