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Telomerase in the ovary

20 Jun 2010

Abstract excerpt

Telomerase, an enzyme complex that binds the chromosome ends (telomeres) and maintains telomere length and integrity, is present in germ cells, proliferative granulosa cells, germline stem cells, and neoplastic cells in the ovary, but it is absent in differentiated or aged cells. Activation of telomerase in the ovary underpins both benign and malignant cell proliferation in several compartments, including the...

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Share to Genetics, Aging, and Longevity in Model Organisms
Share to Reproductive Biology and Fertility
Share to Telomeres, Telomerase, and Senescence

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Identifiers

PMID: 20562297
DOI: 10.1530/rep-10-0008

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