Article
Clinical features of neuromyelitis optica in a large Japanese cohort: comparison between phenotypes.
Journal of neurology, neurosurgery, and psychiatry - 1 Dec 2011
Nagaishi Akiko, Takagi Mineo, Umemura Atsushi, Tanaka Masami, Kitagawa Yoko, Matsui Makoto, Nishizawa Masatoyo, Sakimura Kenji, Tanaka Keiko
Abstract excerpt
OBJECTIVE: To analyse clinicoepidemiological features of neuromyelitis optica in a large cohort and to compare the differences between onset age, gender and clinical phenotypes. METHODS: Antiaquaporin-4 antibody (AQP4-ab) levels were tested in 2366 serum samples of patients diagnosed as having central nervous system inflammatory demyelinating disorders by their referring physicians. AQP4-ab was measured by...
Topics
- Adult
- Age of Onset
- Antibodies
- Aquaporin 4
- Biomarkers
- Brain
- Cohort Studies
- Female
- Humans
- Japan
- Magnetic Resonance Imaging
- Male
- Middle Aged
- Neuroimaging