Article
The use of microcapsules for high density growth of human tumor infiltrating lymphocytes and other immune reactive T cells.
Journal of immunological methods - 9 Feb 1990
Reilly E B, Antognetti G, Wesolowski J S, Sakorafas P
Abstract excerpt
The use of microcapsules to achieve high density growth of tumor infiltrating lymphocytes (TIL) and other antigen-specific human T cells is described. Whereas human T cells in suspension cultures usually do not exceed 1-2 x 10(6) cells/ml, densities approaching that found in living tissues (greater than 10(8) cells/ml) have been observed for microcapsule cultures. TIL and human peripheral blood-derived T cells...
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