Article
Treatment factors rather than genetic variation determine metabolic syndrome in childhood cancer survivors.
European journal of cancer (Oxford, England : 1990) - 1 Feb 2013
van Waas Marjolein, Neggers Sebastian J C M M, Uitterlinden André G, Blijdorp Karin, van der Geest Ivana M M, Pieters Rob, van den Heuvel-Eibrink Marry M
Abstract excerpt
BACKGROUND: Genetic variation that regulates insulin resistance, blood pressure and adiposity in the normal population might determine differential vulnerability for metabolic syndrome after treatment for childhood cancer. OBJECTIVE: To evaluate the contribution of candidate single nucleotide polymorphisms (SNPs) relevant for metabolic syndrome in our single centre cohort of adult long-term childhood cancer...
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