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Article

Impact of molecular diagnosis on treating Mendelian susceptibility to mycobacterial diseases.

Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi - 1 Dec 2012

Wang Li-Hui, Yen Chia-Liang, Chang Tsung-Chain, Liu Ching-Chuan, Shieh Chi-Chang

Abstract excerpt

BACKGROUND/OBJECTIVE: The IL-12-IFN-γ axis is critical for immune defense against mycobacterial infections. Inherited mutations that affect normal activation of this self-amplifying cytokine reaction lead to increased chances of mycobacterial infections, known as Mendelian susceptibility to mycobacterial diseases (MSMD). Delayed diagnosis and difficulty in identifying pathogenic mycobacteria hinder proper...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interferon gamma Receptor

Share to Mycobacterium Infections, Nontuberculous

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Source

Identifiers

PMID: 23036270
DOI: 10.1016/j.jmii.2012.08.017

Genes

IFNGR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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