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Article

Single cell analysis of gene expression patterns during carbon starvation in Bacillus subtilis reveals large phenotypic variation.

Environmental microbiology - 1 Dec 2012

de Jong Imke G, Veening Jan-Willem, Kuipers Oscar P

Abstract excerpt

How cells dynamically respond to fluctuating environmental conditions depends on the architecture and noise of the underlying genetic circuits. Most work characterizing stress pathways in the model bacterium Bacillus subtilis has been performed on bulk cultures using ensemble assays. However, investigating the single cell response to stress is important since noise might generate significant phenotypic...

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PMID: 23033921
DOI: 10.1111/j.1462-2920.2012.02892.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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