Article
The expression and mutation of β-catenin in colorectal traditional serrated adenomas.
Indian journal of pathology & microbiology - 1 Jan 2000
Dai Xiaojun, Wang Luping, Zhang Liying, Han Ying, Yang Guangzhi, Li Lin
Abstract excerpt
CONTEXT: Exon 3 mutation of β-catenin is associated with the carcinogenesis. AIMS: In this study we aimed to detect the expression of exon 3 mutations of β-catenin in colorectal TSA, TA/VTA, and CRC. MATERIALS AND METHODS: Immunohistochemistry staining for β-catenin was performed for 30 TSA, 20 tubular adenomas (TA)/villous tubular adenomas (VTA), and 21 colorectal carcinoma (CRC) cases. DNA sequencing of the...
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