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Article

B-Myb promotes S-phase independently of its sequence-specific DNA binding activity and interacts with polymerase delta-interacting protein 1 (Pdip1).

Cell cycle (Georgetown, Tex.) - 1 Nov 2012

Werwein Eugen, Schmedt Thore, Hoffmann Heiko, Usadel Clemens, Obermann Nora, Singer Jeffrey D, Klempnauer Karl-Heinz

Abstract excerpt

B-Myb is a highly conserved member of the Myb transcription factor family, which plays an essential role in cell cycle progression by regulating the transcription of genes at the G 2/M-phase boundary. The role of B-Myb in other parts of the cell cycle is less well-understood. By employing siRNA-mediated silencing of B-Myb expression, we found that B-Myb is required for efficient entry into S-phase. Surprisingly,...

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Identifiers

PMID: 23032261
DOI: 10.4161/cc.22386
PMCID: PMC3507500

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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