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Article

Chikungunya Virus Replication Rate Determines the Capacity of Crossing Tissue Barriers in Mosquitoes.

Journal of virology - 13 Jan 2021

Merwaiss Fernando, Filomatori Claudia V, Susuki Yasutsugu, Bardossy Eugenia S, Alvarez Diego E, Saleh María-Carla

Abstract excerpt

Chikungunya virus (CHIKV) is a reemerging and rapidly spreading pathogen transmitted by mosquitoes. The emergence of new epidemic variants of the virus is associated with genetic evolutionary traits, including duplication of repeated RNA elements in the 3' untranslated region (UTR) that seemingly favor transmission by mosquitoes. The transmission potential of a given variant results from a complex interplay...

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Identifiers

PMID: 33148794
DOI: 10.1128/JVI.01956-20
PMCID: PMC7925089

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