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Expression of immune inhibitory receptor ILT3 in acute myeloid leukemia with monocytic differentiation

1 Oct 2012

Abstract excerpt

BACKGROUND: The diagnosis of AML with monocytic differentiation is limited by the lack of highly sensitive and specific monocytic markers. Immunoglobulin-like transcript 3 (ILT3) is an immune inhibitory receptor expressed by myelomonocytic cells and at high levels by tolerogenic dendritic cells. METHODS: Using flow cytometry, we analyzed the expression of ILT3 in 37 patients with AML and 20 patients with no...

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PMID: 23027709
DOI: 10.1002/cyto.b.21050

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