Article
An optimized technology platform for the rapid multiplex molecular analysis of genetic alterations associated with leukemia.
Cancer genetics - 1 Oct 2012
Ye Fei, Laosinchai-Wolf Walairat, Labourier Emmanuel
Abstract excerpt
Molecular methods play a critical role in the accurate diagnosis of leukemia by complementing morphologic, cytochemical, immunophenotypic, and cytogenetic analyses. We developed a multiplex reverse transcription-polymerase chain reaction (RT-PCR) method combined with liquid bead array cytometry for the rapid detection of genetic alterations associated with leukemia. Fusion transcripts corresponding to the most...
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