Article
Lysine-71 in the large delta antigen of hepatitis delta virus clade 3 modulates its localization and secretion.
Virus research - 1 Dec 2012
Huang Chi-Ruei, Wang Robert Y L, Hsu Sheng-Chieh, Lo Szecheng J
Abstract excerpt
Hepatitis delta virus (HDV) is an RNA virus and eight clades of HDV have been identified. HDV clade 3 (HDV-3) is isolated only in the northern area of South America. The outcome of HDV-3 infection is associated with severe fulminant hepatitis. Variations in the large delta antigen (LDAg) between HDV clade 1 (HDV-1) and HDV-3 have been proposed to contribute to differences in viral secretion efficiency, but which...
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