Article
Reversion of the ErbB malignant phenotype and the DNA damage response.
Experimental and molecular pathology - 1 Dec 2012
Runkle E Aaron, Zhang Hongtao, Cai Zheng, Zhu Zhiqiang, Karger Barry L, Wu Shiaw-Lin, O'Rourke Donald M, Zhou Zhaocai, Wang Qiang, Greene Mark I
Abstract excerpt
The ErbB or HER family is a group of membrane bound tyrosine kinase receptors that initiate signal transduction cascades, which are critical to a wide range of biological processes. When over-expressed or mutated, members of this kinase family form homomeric or heteromeric kinase assemblies that...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.