Article
Toll-like receptor gene variants associated with bacterial vaginosis among HIV-1 infected adolescents.
Journal of reproductive immunology - 1 Dec 2012
Royse Kathryn E, Kempf Mirjam-Colette, McGwin Gerald, Wilson Craig M, Tang Jianming, Shrestha Sadeep
Abstract excerpt
Bacterial vaginosis (BV) is a common vaginal disorder in women of reproductive age, especially among women with HIV-1 infection. Several bacterial products including lipopolysaccharides (LPS), lipoteichoic acids (LTA), and peptidoglycans (PGN) are stimulatory ligands for Toll-like receptors (TLRs), and recent evidence indicates the important role of variation in TLR genes for permitting overgrowth of gram...
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