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Article

Brief Report: Bacterial Vaginosis and Risk of HIV Infection in the Context of CD101 Gene Variation.

Journal of acquired immune deficiency syndromes (1999) - 15 Dec 2020

Wanga Valentine, Mackelprang Romel D, Thomas Katherine K, Donnell Deborah, Cohen Craig R, Mugo Nelly R, Bukusi Elizabeth A, de Bruyn Guy, Irungu Elizabeth, Celum Connie, Baeten Jared M, Lingappa Jairam R

Abstract excerpt

BACKGROUND: Whether bacterial vaginosis (BV) and CD101 immunoglobulin-like (Ig-like) variants independently increase HIV risk through mucosal inflammation is not well understood. We evaluated whether the impact of BV on HIV acquisition in women differs by the presence or absence of candidate CD101 Ig-like variants. METHODS: We used data from 2 studies of HIV serodiscordant couples in east (Kenya, Tanzania, and...

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Identifiers

PMID: 32976203
DOI: 10.1097/QAI.0000000000002505
PMCID: PMC7654937

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