Article
Relationship between a toll-like receptor-4 gene polymorphism, bacterial vaginosis-related flora and vaginal cytokine responses in pregnant women.
European journal of obstetrics, gynecology, and reproductive biology - 15 Oct 2004
Genc Mehmet R, Vardhana Santosh, Delaney Mary L, Onderdonk Andrew, Tuomala Ruth, Norwitz Errol, Witkin Steven S
Abstract excerpt
OBJECTIVE: The relationship between a single nucleotide polymorphism (TLR4 896 A > G) in the toll-like receptor-4 (TLR4) gene, qualitative and quantitative changes in vaginal micro-flora and vaginal interleukin (IL)-1beta and IL-1 receptor antagonist (IL-1ra) concentrations in pregnant women were evaluated. STUDY DESIGN: Qualitative and quantitative microbial methods were used to characterize vaginal micro-flora...
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