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Article

Massive expansion of the calpain gene family in unicellular eukaryotes.

BMC evolutionary biology - 29 Sept 2012

Zhao Sen, Liang Zhe, Demko Viktor, Wilson Robert, Johansen Wenche, Olsen Odd-Arne, Shalchian-Tabrizi Kamran

Abstract excerpt

BACKGROUND: Calpains are Ca2+-dependent cysteine proteases that participate in a range of crucial cellular processes. Dysfunction of these enzymes may cause, for instance, life-threatening diseases in humans, the loss of sex determination in nematodes and embryo lethality in plants. Although the calpain family is well characterized in animal and plant model organisms, there is a great lack of knowledge about...

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Identifiers

PMID: 23020305
DOI: 10.1186/1471-2148-12-193
PMCID: PMC3563603

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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