Article

Proposed core role for cytosolic and transmembrane calpain cysteine proteases in mitotic cell divisions

2026-05-13

Abstract excerpt

Calpains constitute an ancient, extensive family of calcium-dependent cysteine proteases found in some bacteria and most eukaryotes. They are involved in a wide variety of developmental and cellular processes and are implicated in major human diseases, yet it remains to be seen if they have a common core function explaining their widespread and varied presence across taxa. Beyond their core CysPc catalytic domain,...

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Literature Corpus work: afbb077c-48d7-5cef-9bdd-f013ddf5f69a
DOI: 10.64898/2026.05.11.724225

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