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Virulence in malaria: an evolutionary viewpoint

5 Apr 2004

Abstract excerpt

Malaria parasites cause much morbidity and mortality to their human hosts. From our evolutionary perspective, this is because virulence is positively associated with parasite transmission rate. Natural selection therefore drives virulence upwards, but only to the point where the cost to transmission caused by host death begins to outweigh the transmission benefits. In this review, we summarize data from the...

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PMID: 15306410
DOI: 10.1098/rstb.2003.1414

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