Article
Evolution of quasispecies diversity for porcine reproductive and respiratory syndrome virus under antibody selective pressure.
Science China. Life sciences - 1 Sept 2012
Zhao Peng, Ma ChengTai, Dong Xuan, Cui ZhiZhong
Abstract excerpt
To study the quasispecies diversity of porcine reproductive and respiratory syndrome virus (PRRSV), open reading frame 5 (ORF5) of strain SD0612 was amplified and cloned. Sixty clones of ORF5 were sequenced and analyzed with DNAStar software. Nucleic acid sequence homology was 97.7%-100%, with 78 mutations observed. Among these 60 clones, the sequences of 17 clones were identical and recognized as the dominant...
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