Article
Quasispecies variation of porcine reproductive and respiratory syndrome virus during natural infection.
Virology - 20 Dec 2003
Goldberg Tony L, Lowe James F, Milburn Suzanne M, Firkins Lawrence D
Abstract excerpt
Porcine reproductive and respiratory syndrome virus (PRRSV) displays notorious genetic, antigenic, and clinical variability. Little is known, however, about the nature and extent of viral variation present within naturally infected animals. By amplifying and cloning the open reading frame 5 gene from tonsils of naturally infected swine, and by sequencing individual clones, we characterized viral diversity in nine...
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