Article
Estimating the power of linkage analysis in hereditary breast cancer.
American journal of human genetics - 1 Feb 1990
Narod S A, Amos C
Abstract excerpt
Because evidence from several sources suggests the existence of a major genetic factor contributing to the risk for breast cancer, there is current interest in searching for genetic linkage between the putative cancer susceptibility gene(s) and polymorphic DNA markers. However, because of high population rates of the nongenetic form of the condition, and because of the possibility of underlying genetic...
Topics
- Alleles
- Breast Neoplasms
- Female
- Genetic Carrier Screening
- Genetic Linkage
- Genotype
- Humans
- Male
- Pedigree
- Polymorphism, Genetic
- Probability
- Software