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Article

A bootstrap approach to estimating power for linkage heterogeneity.

Genetic epidemiology - 1 Jan 1993

Leal S M, Ott J

Abstract excerpt

We examined the power of detecting linkage heterogeneity when the null hypothesis is that all families are linked to one locus (A) and the two alternative hypotheses are either 1) a proportion of the families are linked to locus A and the remaining families are linked to a second locus B or 2) a proportion of the families are linked to locus A or B and a third proportion of the families are unlinked to either...

Topics

Aged
Alzheimer Disease
Genetic Linkage
Genetic Variation
Humans
North Carolina
Statistics as Topic

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Identifiers

PMID: 8314045
DOI: 10.1002/gepi.1370100623
PMCID: PMC6141017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8314045-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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