Article
The functional phenotype of the primitive plasma cell in patients with multiple myeloma correlates with the clinical state.
Leukemia & lymphoma - 1 Sept 1997
Pope B, Brown R D, Gibson J, Petersen A, Wiley J, Joshua D E
Abstract excerpt
The malignant plasma cells from patients with multiple myeloma display considerable phenotypic heterogeneity. All plasma cells express high intensity CD38 (CD38++), cytoplasmic immunoglobulin and either kappa or lambda light chains. Subpopulations of mature (CD45-), immature (CD45+) and primitive (CD45++, CD19+) plasma cells can be defined but little is known about the functional differences and clinical...
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