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Circulating cell-free DNA: A promising marker of regional lymphonode metastasis in breast cancer patients

21 Sept 2012

Abstract excerpt

PURPOSE: We undertook the current study with untreated breast cancer to (1) role the variations in the plasma levels of cfDNA and the size distribution in early stage, (2) determine the frequency in plasma of methylation of three candidate genes, RASSF1A, MAL, and SFRP1, and (3) to determine whether detection of cfDNA variations and methylation changes in plasma might have specific clinical utility. METHODS AND...

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PMID: 23011155
DOI: 10.3233/cbm-2012-0263

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