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Levels of plasma circulating cell free nuclear and mitochondrial DNA as potential biomarkers for breast tumors

17 Nov 2009

Abstract excerpt

BACKGROUND: With the aim to simplify cancer management, cancer research lately dedicated itself more and more to discover and develop non-invasive biomarkers. In this connection, circulating cell-free DNA (ccf DNA) seems to be a promising candidate. Altered levels of ccf nuclear DNA (nDNA) and mitochondrial DNA (mtDNA) have been found in several cancer types and might have a diagnostic value. METHODS: Using...

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PMID: 19922604
DOI: 10.1186/1476-4598-8-105

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