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Article

Conserved small protein associates with the multidrug efflux pump AcrB and differentially affects antibiotic resistance.

Proceedings of the National Academy of Sciences of the United States of America - 9 Oct 2012

Hobbs Errett C, Yin Xuefeng, Paul Brian J, Astarita Jillian L, Storz Gisela

Abstract excerpt

The AcrAB-TolC multidrug efflux pump confers resistance to a wide variety of antibiotics and other compounds in Escherichia coli. Here we show that AcrZ (formerly named YbhT), a 49-amino-acid inner membrane protein, associates with the AcrAB-TolC complex. Co-purification of AcrZ with AcrB, in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23010927
DOI: 10.1073/pnas.1210093109
PMCID: PMC3478662

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23010927-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Conserved small protein associates with the multidrug efflux pump AcrB and differentially affects antibiotic resistance.PMID 23010927Read ↗

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