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Article

Comparative multi-goal tradeoffs in systems engineering of microbial metabolism.

BMC systems biology - 26 Sept 2012

Byrne David, Dumitriu Alexandra, Segrè Daniel

Abstract excerpt

BACKGROUND: Metabolic engineering design methodology has evolved from using pathway-centric, random and empirical-based methods to using systems-wide, rational and integrated computational and experimental approaches. Persistent during these advances has been the desire to develop design strategies that address multiple simultaneous engineering goals, such as maximizing productivity, while minimizing raw material...

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Identifiers

PMID: 23009214
DOI: 10.1186/1752-0509-6-127
PMCID: PMC3484036

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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