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Article

Role of Serine140 in the mode of action of Mycobacterium tuberculosis β-ketoacyl-ACP Reductase (MabA).

BMC research notes - 25 Sept 2012

Rosado Leonardo A, Caceres Rafael Andrade, de Azevedo Walter Filgueira, Basso Luiz A, Santos Diógenes S

Abstract excerpt

BACKGROUND: Tuberculosis (TB) still remains one of the most deadly infectious diseases in the world. Mycobacterium tuberculosis β-ketoacyl-ACP Reductase (MabA) is a member of the fatty acid elongation system type II, providing precursors of mycolic acids that are essential to the bacterial cell growth and survival. MabA has been shown to be essential for M. tuberculosis survival and to play a role in...

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Identifiers

PMID: 23006410
DOI: 10.1186/1756-0500-5-526
PMCID: PMC3519566

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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