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Article

Absence of oncogenic canonical pathway mutations in aggressive pediatric rhabdoid tumors.

Pediatric blood & cancer - 15 Dec 2012

Kieran Mark W, Roberts Charles W M, Chi Susan N, Ligon Keith L, Rich Benjamin E, Macconaill Laura E, Garraway Levi A, Biegel Jaclyn A

Abstract excerpt

BACKGROUND: Rhabdoid tumors (also called atypical teratoid/rhabdoid tumor (AT/RT) in the brain), are highly malignant, poor prognosis lesions arising in the kidneys, soft tissues, and central nervous system. Targeted therapy in this disease would benefit from advanced technologies detecting relev...

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Share to Chromosomal Proteins, Non-Histone
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22997201
DOI: 10.1002/pbc.24315
PMCID: PMC3538080

Genes

SMARCB1
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22997201-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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