Article
The XRCC4 rs1805377 polymorphism is not associated with the risk of cancer: An updated meta-analysis.
The Journal of international medical research - 1 Jun 2020
Zhang Xin-Yuan, Wei Xiao-Han, Wang Bao-Jie, Yao Jun
Abstract excerpt
OBJECTIVES: A growing number of studies have reported that genes involved in the repair of DNA double-strand breaks might be cancer-susceptibility genes. The x-ray cross-complementing group 4 gene (XRCC4) encodes a protein that functions in the repair of DNA double-strand breaks, and this meta-analysis aimed to investigate the relationship between the XRCC4 rs1805377 polymorphism and cancer occurrence. METHODS:...
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