Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Translating genetic association of lipid levels for biological and clinical application.

Cardiovascular drugs and therapy - 1 Jun 2021

Crone Bradley, Krause Amelia M, Hornsby Whitney E, Willer Cristen J, Surakka Ida

Abstract excerpt

PURPOSE OF REVIEW: This review focuses on the foundational evidence from the last two decades of lipid genetics research and describes the current status of data-driven approaches for transethnic GWAS, fine-mapping, transcriptome informed fine-mapping, and disease prediction. RECENT FINDINGS: Current lipid genetics research aims to understand the association mechanisms and clinical relevance of lipid loci as well...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apolipoprotein B-100
Share to Dyslipidemias

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Exome Sequencing

Share to Hyperlipidemia, Familial Combined

Share to Lipid Metabolism

Share to Proprotein Convertase 9

Share to Receptors, LDL

Share to Transcriptome

Source

Open in PubMed Open full text

Identifiers

PMID: 33604704
DOI: 10.1007/s10557-021-07156-4
PMCID: PMC8272953

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Translating genetic association of lipid levels for biological and clinical application.PMID 33604704Read ↗

Recent developments in genome and exome-wide analyses of plasma lipids.Semantic proximity Read ↗

Progress in genetic association studies of plasma lipids.Semantic proximity Read ↗

Lipoprotein association studies: taking stock and moving forward.Semantic proximity Read ↗

Whole genome sequence analysis of blood lipid levels in >66,000 individualsSemantic proximity Read ↗

Lipoprotein profile and metabolic fine-mapping of genetic lipid risk lociSemantic proximity Read ↗

Whole genome sequence analysis of blood lipid levels in >66,000 individuals.Semantic proximity Read ↗

The breadth and impact of the Global Lipids Genetics ConsortiumSemantic proximity Read ↗

Genetic determinants of lipid homeostasis.Semantic proximity Read ↗

Discovery and refinement of loci associated with lipid levels.Semantic proximity Read ↗

Multi-Omics Integration Improves Polygenic Risk Prediction for Lipid Traits: A Multi-Ancestry Study in UK Biobank.Semantic proximity Read ↗

The power of genetic diversity in genome-wide association studies of lipids.Semantic proximity Read ↗

Genetically regulated gene expression underlies lipid traits in Hispanic cohortsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.