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Article

[Effect of CYP3A418B, CYP3A53 gene polymorphism on dosage and concentration of tacrolimus in renal transplant patients].

Yao xue xue bao = Acta pharmaceutica Sinica - 1 Jul 2012

Zhu Lin, Song Hong-Tao, Wang Qing-Hua, Wu Wei-Zhen, Yang Shun-Liang, Tan Jian-Ming

Abstract excerpt

The effect of CYP3A4*18B and CYP3A5*3 on concentration/dosage x body surface area ratios (C/D'), adverse effects and acute rejection of tacrolimus in renal transplant patients were investigated. The CYP3A4*18B genotypes of 227 renal transplant patients were determined by PCR-RFLP method. The differences of C/D' ratios, adverse reactions and acute rejection were compared among all of the genotype groups treated...

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Source

Identifiers

PMID: 22993851

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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