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Article

SUMOylation of ATF3 alters its transcriptional activity on regulation of TP53 gene.

Journal of cellular biochemistry - 1 Mar 2013

Wang Chiung-Min, Brennan Victoria C, Gutierrez Ninoska M, Wang Xirui, Wang Lizhong, Yang Wei-Hsiung

Abstract excerpt

Cyclic AMP-dependent transcription factor-3 (ATF3), a stress sensor, plays an essential role in cells to maintain homeostasis and has diverse functions in cellular survival and death signal pathways. ATF3 is a novel regulator of p53 protein stability and function. The activities of ATF3 are modulated by post-translational modifications (PTMs), such as ubiquitination, but whether it is modified by small...

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Source

Identifiers

PMID: 22991139
DOI: 10.1002/jcb.24396

Genes

ATF3
SENP2
SENP7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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