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Article

Regulation of cloned cardiac L-type calcium channels by cGMP-dependent protein kinase.

The Journal of biological chemistry - 3 Mar 2000

Jiang L H, Gawler D J, Hodson N, Milligan C J, Pearson H A, Porter V, Wray D

Abstract excerpt

We have studied the effect of 8-bromo-cyclic GMP (8-Br-cGMP) on cloned cardiac L-type calcium channel currents to determine the site and mechanism of action underlying the functional effect. Rabbit cardiac alpha(1C) subunit, in the presence or absence of beta(1) subunit (rabbit skeletal muscle) or beta(2) subunit (rat cardiac/brain), was expressed in Xenopus oocytes, and two-electrode voltage-clamp recordings...

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Identifiers

PMID: 10692404
DOI: 10.1074/jbc.275.9.6135

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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