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Article

Organotypic brain slice cultures of adult transgenic P301S mice--a model for tauopathy studies.

PloS one - 1 Jan 2012

Mewes Agneta, Franke Heike, Singer David

Abstract excerpt

BACKGROUND: Organotypic brain slice cultures represent an excellent compromise between single cell cultures and complete animal studies, in this way replacing and reducing the number of animal experiments. Organotypic brain slices are widely applied to model neuronal development and regeneration...

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Identifiers

PMID: 22984603
DOI: 10.1371/journal.pone.0045017
PMCID: PMC3439393

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22984603-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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