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Article

Endogenous amyloidogenesis in long-term rat hippocampal cell cultures

10 May 2011

Abstract excerpt

BACKGROUND: Long-term primary neuronal cultures are a useful tool for the investigation of biochemical processes associated with neuronal senescence. Improvements in available technology make it possible to observe maturation of neural cells isolated from different regions of the rodent brain over a prolonged period in vitro. Existing experimental evidence suggests that cellular aging occurs in mature, long-term,...

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PMID: 21569253
DOI: 10.1186/1471-2202-12-38

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