Article
Distribution of beta-thalassemia mutations in the northern provinces of Iran.
Hemoglobin - 1 Jan 2007
Derakhshandeh-Peykar Pupak, Akhavan-Niaki Haleh, Tamaddoni Ahmad, Ghawidel-Parsa Shohreh, Naieni Kourosh Holakouie, Rahmani Manijeh, Babrzadeh Farbod, Dilmaghani-Zadeh Mohammad, Farhud Dariush Daneshvar
Abstract excerpt
Beta-Thalassemia (thal) is one of the most common autosomal recessive disorders in Iran. There are more than two million carriers of beta-thal and over 15,000 people affected with beta-thal major who live in Iran. Prevalent mutations were identified by examining genomic DNAs isolated from 392 blood samples of beta-thal carriers from three northern provinces of Iran. Furthermore, 172 pregnant women were analyzed...
Topics
- DNA Mutational Analysis
- Female
- Frameshift Mutation
- Gene Frequency
- Humans
- Iran
- Male
- Molecular Epidemiology
- Mutation
- Point Mutation
- Pregnancy
- Sequence Deletion
- beta-Thalassemia