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Article

Embryonic demise caused by targeted disruption of a cysteine protease Dub-2.

PloS one - 1 Jan 2012

Baek Kwang-Hyun, Lee Heyjin, Yang Sunmee, Lim Soo-Bin, Lee Wonwoo, Lee Jeoung Eun, Lim Jung-Jin, Jun Kisun, Lee Dong-Ryul, Chung Young

Abstract excerpt

BACKGROUND: A plethora of biological metabolisms are regulated by the mechanisms of ubiquitination, wherein this process is balanced with the action of deubiquitination system. Dub-2 is an IL-2-inducible, immediate-early gene that encodes a deubiquitinating enzyme with growth regulatory activity....

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Identifiers

PMID: 22984479
DOI: 10.1371/journal.pone.0044223
PMCID: PMC3440420

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22984479-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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