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Article

Impact of HIV-1 replication on immunological evolution during long-term dual-boosted protease inhibitor therapy.

Medical microbiology and immunology - 1 Apr 2013

Stephan Christoph, Bartha Valentin, Herrmann Eva, von Hentig Nils, Khaykin Pavel, Knecht Gaby, Gute Peter, Brodt Hans-Reinhard, Stürmer Martin, Berger Annemarie, Bickel Markus

Abstract excerpt

To explore CD4-cell and viral evolution in relation to different levels of HIV-1 replication, as observed during protease inhibitor (PI)-based antiretroviral therapy. Adult HIV-1 infected cohort patients, receiving historical salvage therapy with daily doses of saquinavir (2,000 mg), ritonavir (200 mg) and either lopinavir (800 mg) or atazanavir (300 mg) for >36 weeks were retrospectively analysed for highest...

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Share to Anti-HIV Agents
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22983722
DOI: 10.1007/s00430-012-0276-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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