Predictors of virological outcome and safety in primary HIV type 1-infected patients initiating quadruple antiretroviral therapy: QUEST GW PROB3005.

doi:10.1086/519428

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Predictors of virological outcome and safety in primary HIV type 1-infected patients initiating quadruple antiretroviral therapy: QUEST GW PROB3005.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 1 Aug 2007

Hoen Bruno, Cooper David A, Lampe Fiona C, Perrin Luc, Clumeck Nathan, Phillips Andrew N, Goh Li-Ean, Lindback Stefan, Sereni Daniel, Gazzard Brian, Montaner Julio, Stellbrink Hans-Jurgen, Lazzarin Adriano, Ponscarme Diane, Staszewski Shlomo, Mathiesen Lars, Smith Don, Finlayson Robert, Weber Rainer, Wegmann Laurence, Janossy George, Kinloch-de Loes Sabine

Abstract excerpt

BACKGROUND: Initiation of antiretroviral therapy during primary human immunodeficiency virus (HIV)-1 infection may confer long-term benefit. METHODS: After initiation of zidovudine, lamivudine, abacavir, and amprenavir therapy in patients in the QUEST cohort, predictors of virological outcome, virological and immunological changes, and adverse events were evaluated over 48 weeks. RESULTS: One hundred forty-eight...

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PMID: 17599319
DOI: 10.1086/519428

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