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Article

Microarray, gene sequencing, and reverse transcriptase-polymerase chain reaction analyses of a cryptic PML-RARA translocation.

Cancer genetics - 1 Oct 2012

Koshy Jason, Qian You-Wen, Bhagwath Gayathri, Willis Maurice, Kelley Todd W, Papenhausen Peter

Abstract excerpt

Acute promyelocytic leukemia (APL) is a well-defined subtype of acute myeloid leukemia (AML) specifically characterized by the t(15;17)(q22;q12) translocation. The t(15;17) results in the fusion of the promyelocytic leukemia (PML) and retinoic acid receptor alpha (RARA) genes. Rare cryptic fusion...

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Share to Chromosomes, Human, Pair 15
Share to Chromosomes, Human, Pair 17
Share to Gene Duplication

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Loss of Heterozygosity

Share to Promyelocytic Leukemia Protein

Share to Receptors, Retinoic Acid

Share to Retinoic Acid Receptor alpha

Share to Translocation, Genetic

Source

Identifiers

PMID: 22982005
DOI: 10.1016/j.cancergen.2012.07.017

Genes

PML
RARA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22982005-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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