Article
The transcriptional landscape and mutational profile of lung adenocarcinoma.
Genome research - 1 Nov 2012
Seo Jeong-Sun, Ju Young Seok, Lee Won-Chul, Shin Jong-Yeon, Lee June Koo, Bleazard Thomas, Lee Junho, Jung Yoo Jin, Kim Jung-Oh, Shin Jung-Young, Yu Saet-Byeol, Kim Jihye, Lee Eung-Ryoung, Kang Chang-Hyun, Park In-Kyu, Rhee Hwanseok, Lee Se-Hoon, Kim Jong-Il, Kang Jin-Hyoung, Kim Young Tae
Abstract excerpt
All cancers harbor molecular alterations in their genomes. The transcriptional consequences of these somatic mutations have not yet been comprehensively explored in lung cancer. Here we present the first large scale RNA sequencing study of lung adenocarcinoma, demonstrating its power to identify...
Topics
- Adenocarcinoma
- Exons
- Female
- Gene Expression Regulation, Neoplastic
- Genes, Neoplasm
- Genetic Association Studies
- Humans
- Lung Neoplasms
- Lymphatic Metastasis
- Male