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Article

The Molecular Pathology of Lung Cancer.

Surgical pathology clinics - 1 Sept 2016

Sholl Lynette M

Abstract excerpt

Advances in lung cancer genomics have revolutionized the diagnosis and treatment of this heterogeneous and clinically significant group of tumors. This article provides a broad overview of the most clinically relevant oncogenic alterations in common and rare lung tumors, with an emphasis on the pathologic correlates of the major oncogenic drivers, including EGFR, KRAS, ALK, and MET. Illustrations emphasize the...

Topics

Adenocarcinoma
Biomarkers, Tumor
ErbB Receptors
Humans
Immunohistochemistry
In Situ Hybridization, Fluorescence
Lung Neoplasms
Mutation
Pathology, Molecular
Proto-Oncogene Proteins p21(ras)
Real-Time Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

ras Proteins

Source

Identifiers

PMID: 27523966
DOI: 10.1016/j.path.2016.04.003

Genes

ALK
EGFR
KRAS
MET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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