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Genetic Modeling of Lysosomal Storage Disorders (LSDs), in the Brain-Midgut Axis of <em>Drosophila melanogaster</em>, During Aging

2025-11-21

Abstract excerpt

Lysosomal Storage Disorders (LSDs) are a group of rare inherited diseases caused by mutations in genes encoding proteins involved in normal lysosomal functions, leading to accumulation of undegraded substrates within lysosomes. Among the most prominent clinical features are neurological impairment and neurodegeneration, arising from widespread cellular dysfunction. Development of powerful and reliable animal-model...

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Identifiers and source

Literature Corpus work
805eb652-92f4-59f9-9ec4-5a64522f1d94
DOI
10.20944/preprints202511.1571.v1
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