Article
Genomic inheritances: disclosing individual research results from whole-exome sequencing to deceased participants' relatives.
The American journal of bioethics : AJOB - 1 Jan 2012
Chan Ben, Facio Flavia M, Eidem Haley, Hull Sara Chandros, Biesecker Leslie G, Berkman Benjamin E
Abstract excerpt
Whole-genome analysis and whole-exome analysis generate many more clinically actionable findings than traditional targeted genetic analysis. These findings may be relevant to research participants themselves as well as for members of their families. Though researchers performing genomic analyses are likely to find medically significant genetic variations for nearly every research participant, what they will find...
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