Article
Ethical, legal, and counseling challenges surrounding the return of genetic results in oncology.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 20 May 2013
Lolkema Martijn P, Gadellaa-van Hooijdonk Christa G, Bredenoord Annelien L, Kapitein Peter, Roach Nancy, Cuppen Edwin, Knoers Nine V, Voest Emile E
Abstract excerpt
In the last decade, an overwhelming number of genetic aberrations have been discovered and linked to the development of treatment for cancer. With the rapid advancement of next-generation sequencing (NGS) techniques, it is expected that large-scale DNA analyses will increasingly be used to select patients for treatment with specific anticancer agents. Personalizing cancer treatment has many advantages, but...
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