Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genomics really gets personal: How exome and whole genome sequencing challenge the ethical framework of human genetics research

28 Oct 2011

Abstract excerpt

Exome sequencing (ES) and whole genome sequencing (WGS) putatively identify all adverse functional alleles of protein-coding genes. Accordingly, while ES/WGS are transformative new tools for gene discovery in human and medical genetics research, they also generate new manifestations of ethical issues related to the consent process, data sharing, and return of results. These manifestations have yet to be...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomedical Ethics and Regulation
Share to Ethics in Clinical Research
Share to Genomics and Rare Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22038764
DOI: 10.1002/ajmg.a.34357

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genomics really gets personal: How exome and whole genome sequencing challenge the ethical framework of human genetics researchPMID 22038764Read ↗

The Challenge of Informed Consent and Return of Results in Translational Genomics: Empirical Analysis and RecommendationsSemantic proximity Read ↗

Revealing the results of whole-genome sequencing and whole-exome sequencing in research and clinical investigations: some ethical issues: Table 1Semantic proximity Read ↗

Rethinking the ethical principles of genomic medicine servicesSemantic proximity Read ↗

Informed consent for exome sequencing research in families with genetic disease: The emerging issue of incidental findingsSemantic proximity Read ↗

Tailoring the process of informed consent in genetic and genomic researchSemantic proximity Read ↗

Return of Results in Genomic Research Using Large-Scale or Whole Genome Sequencing: Toward a New NormalSemantic proximity Read ↗

Next generation sequencing in psychiatric research: what study participants need to know about research findings.Semantic proximity Read ↗

Return of individual genomic research results: are laws and policies keeping step?Semantic proximity Read ↗

Translating Personalized Medicine Using New Genetic Technologies in Clinical Practice: The Ethical IssuesSemantic proximity Read ↗

Ethical issues in medical-sequencing research: implications of genotype-phenotype studies for individuals and populations.Semantic proximity Read ↗

Patients' views on incidental findings from clinical exome sequencingSemantic proximity Read ↗

Managing the ethical challenges of next-generation sequencing in genomic medicineSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.