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Article

Role of Scd5, a protein phosphatase-1 targeting protein, in phosphoregulation of Sla1 during endocytosis.

Journal of cell science - 15 Oct 2012

Chi Richard J, Torres Onaidy T, Segarra Verónica A, Lansley Tanya, Chang Ji Suk, Newpher Thomas M, Lemmon Sandra K

Abstract excerpt

Phosphorylation regulates assembly and disassembly of proteins during endocytosis. In yeast, Prk1 and Ark1 phosphorylate factors after vesicle internalization leading to coat disassembly. Scd5, a protein phosphatase-1 (PP1)-targeting subunit, is proposed to regulate dephosphorylation of Prk1/Ark1 substrates to promote new rounds of endocytosis. In this study we analyzed scd5-PP1Δ2, a mutation causing impaired PP1...

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Identifiers

PMID: 22825870
DOI: 10.1242/jcs.098871
PMCID: PMC3517093

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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